Periodontal regeneration: is it still a goal in clinical periodontology?

In the last decades, Periodontal Regeneration has been one of most discussed topics in Periodontics, attracting attention researchers and clinicians. This can be justified by evident continuous progress observed field, characterized a better understanding biological mechanisms involved, significant improvement operative technical principles, emergence wide range biomaterials available for this purpose. Together, these aspects put theme much evidence search functional esthetic therapeutic solutions periodontal tissue destruction. Despite evolution, regeneration may challenging require clinician to carefully evaluate each case before making decision. With critical reassessment clinical preclinical literature, present study aimed discuss topic answer whether is still goal periodontology. The main involved probability success or failure regenerative approaches were considered. A greater focus was given intrabony furcation defects, conditions with predictability. Aspects such as more appropriate materials/approaches, long-term benefits their justification higher initial cost condition. general, deep defects associated residual pockets buccal/lingual class II lesions have predictable clinically relevant results. Careful selection (based on patient defect characteristics) excellent maintenance are essential ensure success.